Gary Cooper ( Gary Cooper )

Henry Louis 'Lou' Gehrig

Teresa Wright ( Teresa Wright )

Eleanor Twitchell

Babe Ruth ( Babe Ruth )

Babe Ruth

Walter Brennan ( Walter Brennan )

Sam Blake

Dan Duryea ( Dan Duryea )

Hank Hanneman

Elsa Janssen ( Elsa Janssen )

Christina 'Mom' Gehrig

Ludwig Stössel ( Ludwig Stössel )

Henry 'Pop' Gehrig

Virginia Gilmore ( Virginia Gilmore )

Myra Tinsley

Bill Dickey ( Bill Dickey )

Bill Dickey

Ernie Adams ( Ernie Adams )

Miller Huggins

Pierre Watkin ( Pierre Watkin )

Mr. Twitchell

Harry Harvey ( Harry Harvey )

Joe McCarthy

Bob Meusel ( Bob Meusel )

Robert W. Meusel (as Robert W. Meusel)

Mark Koenig ( Mark Koenig )

Mark Koenig

Bill Stern ( Bill Stern )

Bill Stern

Addison Richards ( Addison Richards )

Coach

Hardie Albright ( Hardie Albright )

Van Tuyl

Edward Fielding ( Edward Fielding )

Clinic Doctor

George Lessey ( George Lessey )

Mayor of New Rochelle

Edgar Barrier ( Edgar Barrier )

Hospital Doctor

Douglas Croft ( Douglas Croft )

Lou Gehrig as a Boy

Gene Collins ( Gene Collins )

Billy (Age 8)

David Holt ( David Holt )

Billy (Age 17)

Veloz ( Veloz )

Specialty Dancer (as Veloz and Yolanda)

Yolanda ( Yolanda )

Specialty Dancer (as Veloz and Yolanda)

Ed Agresti ( Ed Agresti )

Barber (uncredited)

Ernie Alexander ( Ernie Alexander )

Bellhop with Flowers (uncredited)

Hooper Atchley ( Hooper Atchley )

Lathered Man in Barber Shop (uncredited)

Edwin August ( Edwin August )

Restaurant Patron (uncredited)

Bettye Avery ( Bettye Avery )

Nightclub Singer (uncredited)

Becky Bohanon ( Becky Bohanon )

Little Girl (uncredited)

Lynton Brent ( Lynton Brent )

Photographer in Hospital (uncredited)

Roy Brent ( Roy Brent )

Yankee Ballplayer (uncredited)

Betty Brewer ( Betty Brewer )

Little Girl (uncredited)

Don Brodie ( Don Brodie )

Girl Show Barker (uncredited)

Charles Cane ( Charles Cane )

Plumber (uncredited)

Jack Carr ( Jack Carr )

Plumber (uncredited)

Burr Caruth ( Burr Caruth )

Village Storekeeper (uncredited)

Eddy Chandler ( Eddy Chandler )

Motorcycle Cop #2 (uncredited)

Lane Chandler ( Lane Chandler )

Mark - Player in Locker Room (uncredited)

Bill Chaney ( Bill Chaney )

Newsboy (uncredited)

Jack Chapin ( Jack Chapin )

Photographer (uncredited)

Janet Chapman ( Janet Chapman )

Tessie (uncredited)

Spencer Charters ( Spencer Charters )

Mr. Larsen (uncredited)

Porter Chase ( Porter Chase )

Weight Guesser (uncredited)

Dane Clark ( Dane Clark )

Fraternity Boy (uncredited)

Heinie Conklin ( Heinie Conklin )

Wallpaper Hanger (uncredited)

Hal Cooke ( Hal Cooke )

Man in Cab (uncredited)

Clancy Cooper ( Clancy Cooper )

Motorcycle Cop #1 (uncredited)

John Daheim ( John Daheim )

Reporter in Hospital (uncredited)

Eva Dennison ( Eva Dennison )

Mrs. Worthington (uncredited)

Lester Dorr ( Lester Dorr )

Disappointed Fan #1 (uncredited)

Peter Du Rey ( Peter Du Rey )

Photographer in Hospital (uncredited)

Lorna Dunn ( Lorna Dunn )

Clinic Nurse (uncredited)

Jim Farley ( Jim Farley )

Spectator (uncredited)

Frank Faylen ( Frank Faylen )

Yankee Third Base Coach (uncredited)

Walter Fenner ( Walter Fenner )

Dentist (uncredited)

Pat Flaherty ( Pat Flaherty )

Yankee Ballplayer (uncredited)

Rosina Galli ( Rosina Galli )

Mrs. Fabrini (uncredited)

Vaughan Glaser ( Vaughan Glaser )

Doctor in Gehrig Home (uncredited)

Dick Gordon ( Dick Gordon )

Radio Listener (uncredited)

Mary Gordon ( Mary Gordon )

Maid (uncredited)

Herschel Graham ( Herschel Graham )

Spectator (uncredited)

George Guhl ( George Guhl )

Second Paper Hanger (uncredited)

Eddie Hall ( Eddie Hall )

Reporter in Hospital Room (uncredited)

Harry Hayden ( Harry Hayden )

Department Store Manager (uncredited)

Vinton Hayworth ( Vinton Hayworth )

Fraternity Boy (uncredited)

Oscar 'Dutch' Hendrian ( Oscar 'Dutch' Hendrian )

Furniture Mover (uncredited)

John Hiestand ( John Hiestand )

Announcer (uncredited)

Earle Hodgins ( Earle Hodgins )

Bottle Game Operator (uncredited)

Fay Holderness ( Fay Holderness )

Spectator (uncredited)

John Ince ( John Ince )

Man in Box Seat (uncredited)

Mitchell Ingraham ( Mitchell Ingraham )

Barber (uncredited)

Charles Irwin ( Charles Irwin )

Carnival Batting Game Operator (uncredited)

Jack Irwin ( Jack Irwin )

Photographer in Hospital (uncredited)

Sheldon Jett ( Sheldon Jett )

Sportsman at Ballgame (uncredited)

Payne B. Johnson ( Payne B. Johnson )

Boy in Ball Park (uncredited)

John Kellogg ( John Kellogg )

Fraternity Boy (uncredited)

Colin Kenny ( Colin Kenny )

Yankee Player on Train (uncredited)

Donald Kerr ( Donald Kerr )

Photographer (uncredited)

Richard Kipling ( Richard Kipling )

Broker (uncredited)

Pat Lane ( Pat Lane )

Wheel of Chance Barker (uncredited)

Larry Lawson ( Larry Lawson )

Barker (uncredited)

Rex Lease ( Rex Lease )

Spectator (uncredited)

Theodore Lorch ( Theodore Lorch )

Neighbor Leaning Through Window (uncredited)

Frank Lyman ( Frank Lyman )

Fraternity Boy (uncredited)

Wilbur Mack ( Wilbur Mack )

Man Outside Yankee Stadium (uncredited)

Dave Manley ( Dave Manley )

Mayor Fiorello LaGuardia (uncredited)

Maurice Marks ( Maurice Marks )

Player (uncredited)

Francisco Marán ( Francisco Marán )

Rathskeller Headwaiter (uncredited)

John C. McCallum ( John C. McCallum )

Minor Role (uncredited)

Ralph McCullough ( Ralph McCullough )

Reporter in Hospital (uncredited)

George McDonald ( George McDonald )

Wally Pipp (uncredited)

Matt McHugh ( Matt McHugh )

Strength Machine Operator (uncredited)

James McNamara ( James McNamara )

Rathskeller Manager (uncredited)

Wilmuth Merkyl ( Wilmuth Merkyl )

Spectator (uncredited)

Howard M. Mitchell ( Howard M. Mitchell )

Sportsman at Ballgame (uncredited)

Irving Mitchell ( Irving Mitchell )

Headwaiter (uncredited)

Pat Moriarity ( Pat Moriarity )

Policeman in 1915 (uncredited)

Tom Neal ( Tom Neal )

Fraternity Boy (uncredited)

Ray Noble ( Ray Noble )

Orchestra Leader (uncredited)

Patsy O'Byrne ( Patsy O'Byrne )

Scrubwoman (uncredited)

George Offerman, Jr. ( George Offerman, Jr. )

Freshman (uncredited)

John B. Old ( John B. Old )

Reporter (uncredited)

Garry Owen ( Garry Owen )

Scorecard Vendor (uncredited)

Sarah Padden ( Sarah Padden )

Mrs. Roberts (uncredited)

Emory Parnell ( Emory Parnell )

Chicago Policeman O'Doul (uncredited)

Edward Peil Sr. ( Edward Peil Sr. )

Policeman (uncredited)

Tom Quinn ( Tom Quinn )

Reporter in Hospital (uncredited)

Cyril Ring ( Cyril Ring )

Photographer (uncredited)

Henry Roquemore ( Henry Roquemore )

Disappointed Fan #2 (uncredited)

Art Rowlands ( Art Rowlands )

Telephone Man (uncredited)

William Roy ( William Roy )

Joe Fabrini (uncredited)

Rip Russell ( Rip Russell )

Laddie (uncredited)

Francis Sayles ( Francis Sayles )

Cab Driver (uncredited)

Anita Sharp-Bolster ( Anita Sharp-Bolster )

Sasha's Mother (uncredited)

C. Montague Shaw ( C. Montague Shaw )

Mr. Worthington (uncredited)

Jack Shea ( Jack Shea )

Hammond (uncredited)

John Sheehan ( John Sheehan )

First Paper Hanger (uncredited)

Jack Stewart ( Jack Stewart )

Ed Barrow (uncredited)

Brick Sullivan ( Brick Sullivan )

Policeman (uncredited)

Ben Taggart ( Ben Taggart )

Conductor (uncredited)

Walter Tetley ( Walter Tetley )

Cake Delivery Boy (uncredited)

Jimmy Valentine ( Jimmy Valentine )

Sasha - Boy Playing Baseball (uncredited)

Gohr Van Vleck ( Gohr Van Vleck )

Furniture Mover (uncredited)

Dorothy Vaughan ( Dorothy Vaughan )

Eleanor's Landlady (uncredited)

Dorothy Vernon ( Dorothy Vernon )

Family Friend (uncredited)

Malcolm Waite ( Malcolm Waite )

Big Strength Machine Contestant (uncredited)

James Westerfield ( James Westerfield )

Spectator (uncredited)

Guy Wilkerson ( Guy Wilkerson )

Sportsman at Ballgame (uncredited)

Max Willenz ( Max Willenz )

Mr. Colletti (uncredited)

Buddy Williams ( Buddy Williams )

Bootblack (uncredited)

Charles Williams ( Charles Williams )

Little Strength Machine Contestant (uncredited)

Robert Winkler ( Robert Winkler )

Murphy (uncredited)

Allen Wood ( Allen Wood )

Freshman (uncredited)

Mike Donovan ( Mike Donovan )

Dick Gordon ( Dick Gordon )

Radio Listener (uncredited)

Charles Flynn ( Charles Flynn )

Fraternity Boy (uncredited)

Jack Gardner ( Jack Gardner )

Anthony Walters ( Anthony Walters )

Merril (uncredited)